Trypsin 1/PRSS1 Antibody (2C4) - BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2C4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Trypsin 1/PRSS1 Antibody (2C4) - BSA Free Summary

Immunogen
Trypsin purified from human pancreatic tissue and adsorbed onto aluminum hydroxide gel (2)
Specificity
Specific for human trypsin, trypsinogen and trypsin in complex with alpha-1-antitrypsin. Cross reacts weakly with bovine trypsin.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PRSS1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:8000

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM Phosphate (pH 7.4) and 0.5M NaCl
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for Trypsin 1/PRSS1 Antibody (2C4) - BSA Free

  • Beta-trypsin
  • Cationic trypsinogen
  • digestive zymogen
  • DKFZp779A0837
  • EC 3.4.21
  • EC 3.4.21.4
  • FLJ57296
  • MGC120175
  • MGC149362
  • nonfunctional trypsin 1
  • protease, serine, 1 (trypsin 1)
  • PRSS1
  • PTRYI
  • Serine protease 1
  • TRP1
  • TRY1beta-trypsin
  • TRY4
  • Trygn16
  • TRYP1
  • Trypsin 1
  • Trypsin I
  • trypsin-1
  • Trypsinogen 1
  • trypsinogen A

Background

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen. The active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin predominantly cleaves proteins at the carboxyl side of the amino acids lysine and arginine. A common trypsin substrate is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PRSS1
Entrez