TRUSS Antibody

Western Blot: TRUSS Antibody [NBP1-45204] - Analysis of TRUSS (1ug/ml) staining of U937 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

TRUSS Antibody Summary

• Description: Novus Biologicals Goat TRUSS Antibody (NBP1-45204) is a polyclonal antibody validated for use in WB and ELISA. Anti-TRUSS Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-KLTQETTYPNTYIFD corresponding to internal region according to NP_056453.1, NP_955400.1.
• Epitope: internal region
• Marker: Myelinated Neurons Marker
• Specificity: This antibody is expected to recognize both reported isoforms (NP_955400.1; NP_056453.1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TRPC4AP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:4000
  • Western Blot 1 - 3 ug/ml
• Application Notes: WB: Approx. 85 kDa band observed in lysates of U937 (calculated MW of 90.0 kDa band according to human NP_056453.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TRUSS Antibody

• C20orf188
• dJ756N5.2
• DKFZp586C1223
• DKFZP727M231
• Protein TAP1
• Protein TRUSS
• short transient receptor potential channel 4 associated protein
• short transient receptor potential channel 4-associated protein
• TNF-receptor ubiquitous scaffolding/signaling protein
• transient receptor potential cation channel, subfamily C, member 4 associatedprotein
• Trp4-associated protein
• Trpc4-associated protein
• TRRP4APchromosome 20 open reading frame 188
• TRUSS
• tumor necrosis factor receptor-associated ubiquitous scaffolding and signalingprotein

Background

FUNCTION: May participate in the activation of NFKB1 in response to ligation of TNFRSF1A. Could serve as a scaffolding protein to link TNFRSF1A to the IKK signalosome. SUBUNIT: Constitutively associated with TNFRSF1A. Directly interacts with TRADD, TRAF2, CHUK, IKBKB and IKBKG.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TRUSS Antibody (NBP1-45204)(1)

Publication using NBP1-45204

• Poduslo SE, Huang R, Huang J, Smith S. Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis. Am J Med Genet B Neuropsychiatr Genet 2009-01-05 [PMID: 18449908]

Bioinformatics

• Gene Symbol: TRPC4AP
• Entrez:
  • 26133(Human)
• Uniprot:
  • NP_056453.1(Human)