TRIM29 Antibody (TRIM29/1041)

Immunohistochemistry-Paraffin: TRIM29 Antibody (TRIM29/1041) [NBP2-44403] - Human Lung Squamous Cell Carcinoma stained with TRIM29 Monoclonal Antibody (TRIM29/1041).

Immunohistochemistry-Paraffin: TRIM29 Antibody (TRIM29/1041) [NBP2-44403] - Human Esophageal carcinoma stained with TRIM29 Monoclonal Antibody (TRIM29/1041).

• Reactivity: Hu
• Applications: ELISA, IHC
• Clone: TRIM29/1041
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

TRIM29 Antibody (TRIM29/1041) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-47808)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
• Immunogen: Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein (Uniprot: Q14134)
• Localization: Cytoplasmic & Cell Surface
• Marker: Lung Squamous Cell Carcinoma Marker
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TRIM29
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1-2 ug/ml
• Application Notes: ELISA: For coating, order Ab without BSA.
  Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
  Optimal dilution for a specific application should be determined.
• Theoretical MW: 66 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for TRIM29 Antibody (TRIM29/1041)

• Ataxia telangiectasia group D-associated protein
• ATDC ataxia-telangiectasia group D-associated protein
• ATDC
• FLJ36085
• tripartite motif containing 29
• tripartite motif protein TRIM29
• tripartite motif-containing 29
• tripartite motif-containing protein 29

Background

TRIM29 is encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRIM29
• Uniprot:
  • Q14134(Human)