TRAX Antibody

Product Discontinued

TRAX Antibody Summary

• Immunogen: Synthetic peptide, C-KENKTPSSDAQDKQ, representing the internal region of the human protein according to NP_005990.1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TSNAX
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA 1:1000
• Application Notes: Peptide ELISA: antibody detection limit dilution 1:1000. Western Blot: Preliminary experiments in Human Brain gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?

Reactivity Notes

Human and Dog.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for TRAX Antibody

• DISC1
• translin-associated factor Xdisrupted in schizophrenia 1
• translin-like protein
• TRAXtranslin-associated protein X

Background

Translin (TSN) is a DNA-binding protein that specifically binds to consensus sequences at breakpoint junctions of chromosomal translocations in many cases of lymphoid malignancies. TRAX (translin-associated factor X)was isolated as a protein that specifically interacted with TSN in cotransformation and in vitro interaction assays. TRAX bears a homology to Translin. Translin and TRAX have been proposed to be involved in DNA recombination, chromosomal translocation and mRNA transport and translation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TSNAX
• Entrez:
  • 7257(Human)
• Uniprot:
  • NP_005990.1(Human)