TR4/NR2C2 Antibody

Western Blot: TR4/NR2C2 Antibody [NBP2-19579] - Sample (30 ug of whole cell lysate) A: Hela 7. 5% SDS PAGE gel, diluted at 1:1000.

Product Discontinued

TR4/NR2C2 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human NR2C2. The exact sequence is proprietary.
• Localization: Nucleus
• Predicted Species: Mouse (95%), Rat (95%), Bovine (97%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NR2C2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 65 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Zebrafish (80%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for TR4/NR2C2 Antibody

• hTAK1
• NR2C2
• Nuclear hormone receptor TR4
• nuclear receptor subfamily 2 group C member 2
• nuclear receptor subfamily 2, group C, member 2
• Orphan nuclear receptor TAK1
• Orphan nuclear receptor TR4
• TAK1
• TAK1TR4TR2R1
• Testicular receptor 4
• TR4 nuclear hormone receptor
• TR4

Background

Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: NR2C2