TR4/NR2C2 Antibody

Western Blot: TR4/NR2C2 Antibody [NBP1-48315] - Rat Cerebellum Lysate showing specific immunolabeling of the ~64k NR2C2 protein.

Product Discontinued

TR4/NR2C2 Antibody Summary

• Immunogen: Fusion protein from the N-terminal region of mouse TR4
• Specificity: Specific for the ~64 kDa TR4 protein by Western blot in cerebellum and nuclear extracts from MEL cell lines.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NR2C2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Theoretical MW: 64 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Neat whole antisera
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for TR4/NR2C2 Antibody

• hTAK1
• NR2C2
• Nuclear hormone receptor TR4
• nuclear receptor subfamily 2 group C member 2
• nuclear receptor subfamily 2, group C, member 2
• Orphan nuclear receptor TAK1
• Orphan nuclear receptor TR4
• TAK1
• TAK1TR4TR2R1
• Testicular receptor 4
• TR4 nuclear hormone receptor
• TR4

Background

Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR2C2
• Entrez:
  • 22026(Rat)
• Uniprot:
  • P49117(Mouse)