TOP1MT Antibody (TOP1MT/488) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
TOP1MT/488
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 750

Order Details

TOP1MT Antibody (TOP1MT/488) [Alexa Fluor® 750] Summary

Immunogen
Recombinant full-length human TOP1MT protein
Localization
Cytoplasmic (Mitochondria)
Specificity
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TOP1MT
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TOP1MT Antibody (TOP1MT/488) [Alexa Fluor® 750]

  • mitochondrial DNA topoisomerase I
  • mitochondrial
  • topoisomerase (DNA) I, mitochondrial

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47793AF350
Alexa Fluor 405 NBP2-47793AF405
Alexa Fluor 488 NBP2-47793AF488
Alexa Fluor 532 NBP2-47793AF532
Alexa Fluor 594 NBP2-47793AF594
Alexa Fluor 647 NBP2-47793AF647
Alexa Fluor 700 NBP2-47793AF700
Alexa Fluor 750 NBP2-47793AF750
Allophycocyanin NBP2-47793APC
Allophycocyanin/Cy7 NBP2-47793APCCY7
Biotin NBP2-47793B
DyLight 350 NBP2-47793UV
DyLight 405 NBP2-47793V
DyLight 488 NBP2-47793G
DyLight 550 NBP2-47793R
DyLight 594 NBP2-47793DL594
DyLight 650 NBP2-47793C
DyLight 680 NBP2-47793FR
DyLight 755 NBP2-47793IR
FITC NBP2-47793F
HRP NBP2-47793H
Janelia Fluor 549 NBP2-47793JF549
Janelia Fluor 646 NBP2-47793JF646
PE NBP2-47793PE
PE/Atto594 NBP2-47793PEATT594
PE/Cy5.5 NBP2-47793PECY55
PE/Cy7 NBP2-47793PECY7
PerCP NBP2-47793PCP

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Bioinformatics Tool for TOP1MT Antibody (NBP2-47793AF750)

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Blogs on TOP1MT

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol TOP1MT