TNIP2 Antibody [DyLight 550]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 550

TNIP2 Antibody [DyLight 550] Summary

• Immunogen: TNFAIP3 interacting protein 2. (Uniprot# Q8NFZ5)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TNIP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TNIP2 Antibody [DyLight 550]

• A20-binding inhibitor of NF-kappa-B activation 2
• A20-binding inhibitor of NF-kappaB activation-2
• ABIN-2
• ABIN2KLIP
• Fetal liver LKB1-interacting protein
• FLIP1DKFZp434J1313
• MGC4289
• TNFAIP3 interacting protein 2
• TNFAIP3-interacting protein 2

Background

ABIN-2, TNFAIP3 interacting protein 2, binds to the COOH-terminal zinc finger domain of A20. NF-kB activation induced by TNF and interleukin-1 is inhibited by overexpression of ABIN-2. The latter also inhibits NF-kB activation induced by overexpression of receptor-interacting protein or TNF receptor-associated factor 2. A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB)Activation (ABIN-2) binds to A-20. ABIN-2 interferes with NF-kB activation upstream of the IKK complex and might contribute to NF-kB inhibitory function of A-20.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNIP2