TMEFF2/Tomoregulin-2 Antibody (OTI1F9) [mFluor Violet 450 SE]

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clone: OTI1F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

TMEFF2/Tomoregulin-2 Antibody (OTI1F9) [mFluor Violet 450 SE] Summary

• Immunogen: Full length human recombinant protein of human TMEFF2(NP_057276) produced in HEK293T cell.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: TMEFF2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TMEFF2/Tomoregulin-2 Antibody (OTI1F9) [mFluor Violet 450 SE]

• CT120.2
• HPP1member 2
• Hyperplastic polyposis protein 1
• TENB2
• TMEFF2
• Tomoregulin2
• Tomoregulin-2
• TPEFtomoregulin
• TR-2
• transmembrane protein TENB2
• transmembrane protein with EGF-like and two follistatin-like domains 2
• Transmembrane protein with EGF-like and two follistatin-like domains
• TRtomoregulin-2

Background

TMEFF2(transmembrane protein with EGF-like and two follistatin-like domains 2), a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor-like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5' region. Clone J4B6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TMEFF2 protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TMEFF2