TIP120B Antibody [Janelia Fluor® 549]

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 549

TIP120B Antibody [Janelia Fluor® 549] Summary

• Immunogen: The immunogen this antibody was made to, maps to a region between residue 1186 to 1236 of human Cullin-Sssociated and Neddylation-Dissociated 2 using the numbering given in entry NP_001155971.1 (GeneID 23066).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAND2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TIP120B Antibody [Janelia Fluor® 549]

• cullin-associated and neddylation-dissociated 2 (putative)
• Cullin-associated and neddylation-dissociated protein 2
• cullin-associated NEDD8-dissociated protein 2
• epididymis tissue protein Li 169
• KIAA0667TBP-interacting protein of 120 kDa B
• p120 CAND2
• TBP interacting protein
• TBP-interacting protein 120B
• TIP120BTp120b

Background

CAND2 is also known as TIP120B, and TATA-binding protein-interacting protein 120B. While both CAND1 (TIP120A) and CAND2 (TIP120B) are TATA-binding proteins and form complexes with various nuclear proteins involved in the control of eukaryotic gene transcription, CAND2 (TIP120B) is expressed specifically in muscle and heart tissue. This is contrary to the ubiquitous expression of CAND1 (TIP120A). TIP120 homologs exist in various higher eukaryotes including D. melanogaster, C. elegans, and A. thaliana. TIP120B is 60% identical in amino acid sequence to TIP120A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CAND2