TGR5/GPBAR1 Antibody (409522) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Clone: 409522
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

TGR5/GPBAR1 Antibody (409522) [Alexa Fluor™ Plus 594] Summary

• Specificity: Stains human TGR5/GPBAR1 transfectants but not irrelevant transfectants.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TGR5/GPBAR1 Antibody (409522) [Alexa Fluor™ Plus 594]

• BG37
• BG37hBG37
• G protein-coupled bile acid receptor 1
• GPBA
• GPBAR1
• GPCR19
• GPR131
• G-protein coupled bile acid receptor 1
• G-protein coupled bile acid receptor BG37
• G-protein coupled receptor GPCR19
• M-BAR
• M-BARhGPCR19
• membrane bile acid receptor
• Membrane-type receptor for bile acids
• MGC40597
• TGR5
• TGR5GPCR

Background

G protein coupled bile acid receptor 1 (GPBAR1), also called M-BAR, BG37 or TGR5, is a G-protein coupled receptor superfamily member that is a widely expressed cell surface receptor for bile acids. On macrophages, bile acid engagement of GPBAR1 suppresses phagocytosis and other functions. Extracellular portions of human GPBAR1 show approximately 75% amino acid identity with corresponding regions of mouse GPBAR1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.