TfR (Transferrin R) Antibody (66IG10) [PerCP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC-Fr
Clone
66IG10
Clonality
Monoclonal
Host
Mouse
Conjugate
PerCP

TfR (Transferrin R) Antibody (66IG10) [PerCP] Summary

Immunogen
Human thymocytes (T-cells)
Localization
Cell surface
Specificity
It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TFRC
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TfR (Transferrin R) Antibody (66IG10) [PerCP]

  • CD71 antigen
  • CD71
  • CD71TRFR
  • p90
  • T9
  • TfR (Transferrin R)
  • TfR (TransferrinR)
  • TfR
  • TFR1
  • TFRC
  • TR
  • transferrin receptor (p90, CD71)
  • transferrin receptor protein 1
  • TRFR

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional TfR (Transferrin R) Products

Bioinformatics Tool for TfR (Transferrin R) Antibody (NBP2-34542PCP)

Discover related pathways, diseases and genes to TfR (Transferrin R) Antibody (NBP2-34542PCP). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TfR (Transferrin R) Antibody (NBP2-34542PCP)

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Pathways for TfR (Transferrin R) Antibody (NBP2-34542PCP)

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PTMs for TfR (Transferrin R) Antibody (NBP2-34542PCP)

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Research Areas for TfR (Transferrin R) Antibody (NBP2-34542PCP)

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Blogs on TfR (Transferrin R).

Transferrin and the blood brain barrier
Transferrin, an iron binding protein that facilitates iron uptake in cells, is an integral part of a mechanism that may introduce antibody therapies to the central nervous system. Currently, the brain’s ability to take in antibody therapies i...  Read full blog post.

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Bioinformatics

Gene Symbol TFRC
Entrez