TFF2 Antibody (HSP GE16C)

Product Discontinued

TFF2 Antibody (HSP GE16C) Summary

• Immunogen: Synthetic peptide corresponding to a 16 amino acid C-terminal sequence of the human Trefoil factor 2.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: TFF2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin
• Application Notes: Positive control(s): Stomach or duodenum. Not recommended for WB. Use in Immunohistochemistry-paraffin reported in scientific literature (PMID: 30324235).
• Theoretical MW: 14 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 2 mg/ml
• Purity: Protein G purified

Alternate Names for TFF2 Antibody (HSP GE16C)

• SML1
• SML1trefoil factor 2, SML1, human spasmolytic polypeptide (SP)10spasmolytic protein 1
• SP
• Spasmolysin
• Spasmolytic Polypeptide
• TFF2
• trefoil factor 2

Background

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TFF2 Antibody (NBP2-50334)(1)

Publication using NBP2-50334

• Asaka S, Nakajima T, Momose M et al. Trefoil factor family 2 protein: a potential immunohistochemical marker for aiding diagnosis of lobular endocervical glandular hyperplasia and gastric-type adenocarcinoma of the uterine cervix. Virchows Arch. 2018-10-15 [PMID: 30324235] (IHC-P, Human)

Bioinformatics

• Gene Symbol: TFF2