Recombinant Human TDO2 Protein

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SDS-Page: Recombinant Human TDO2 Protein [NBP1-51014] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

Recombinant Human TDO2 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-406 of Human TDO2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSGCPFLGNN FGYTFKKLPV EGSEEDKSQT GVNRASKGGL IYGNYLHLEK VLNAQELQSE TKGNKIHDEH LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VVSRMHRVSV ILKLLVQQFS ILETMTALDF NDFREYLSPA SGFQSLQFRL LENKIGVLQN MRVPYNRRHY RDNFKGEENE LLLKSEQEKT LLELVEAWLE RTPGLEPHGF NFWGKLEKNI TRGLEEEFIR IQAKEESEEK EEQVAEFQKQ KEVLLSLFDE KRHEHLLSKG ERRLSYRALQ GALMIYFYRE EPRFQVPFQL LTSLMDIDSL MTKWRYNHVC MVHRMLGSKA GTGGSSGYHY LRSTVSDRYK VFVDLFNLST YLIPRHWIPK MNPTIHKFLY TAEYCDSSYF SSDESD

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
TDO2
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human TDO2 Protein

  • chky
  • TDO
  • TDO2
  • TDOTO
  • TO
  • TPH2EC 1.13.11.11
  • TRPO
  • TRPOtryptophanase
  • Tryptamin 2,3-dioxygenase
  • tryptophan 2,3-dioxygenase
  • Tryptophan Oxygenase
  • Tryptophan Pyrrolase
  • Tryptophanase

Background

TDO2, also known as TDO, is a ferrous heme enzyme that catalyzes the first and rate-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. It incorporates oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. Recombinant human TDO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for TDO2 Protein (NBP1-51014) (0)

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FAQs for TDO2 Protein (NBP1-51014). (Showing 1 - 1 of 1 FAQ).

  1. Would you have any data concerning the activity of your current lots of TDO protein (cat# NBP1-51014).
    • This TDO2 protein has only been tested for SDS-PAGE. We have no data on the functionality of this protein, and would not recommend it for that use.

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Bioinformatics

Gene Symbol TDO2
Entrez