TCP1-beta Antibody [Janelia Fluor® 669]

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 669

TCP1-beta Antibody [Janelia Fluor® 669] Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-535 of human TCP1-beta (NP_006422.1).
  
  Sequence:
  GGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCT2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TCP1-beta Antibody [Janelia Fluor® 669]

• Cctb
• CCT-beta
• CCTBPRO1633,99D8.1
• chaperonin containing t-complex polypeptide 1, beta subunit
• chaperonin containing t-complex polypeptide 1, subunit 2
• chaperonin containing TCP1, subunit 2 (beta)
• MGC142074
• MGC142076
• T-complex protein 1 subunit beta
• T-complex protein 1, beta subunit
• TCP-1-beta

Background

TCP1-beta encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCT2