TCP1-beta Antibody (F39 P7 F11) - BSA Free

Immunohistochemistry: TCP1-beta Antibody (F39 P7 F11) [NBP2-66591] - Left and Center: Immunohistochemical staining of normal (left) and cancerous (center) colon tissue using TCP-1 beta antibody (Cat. No. NBP2-66591).Right: Western blot analysis using TCP-1 beta antibody on Calu6 (1) and HT-29 (2) cell lysates.

• Reactivity: Hu, Mu, Rt, Xp
• Applications: WB, IHC
• Clone: F39 P7 F11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

TCP1-beta Antibody (F39 P7 F11) - BSA Free Summary

• Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminal of the TCP1-beta protein (Uniprot: P47207) and mouse myeloma Ag8563 cells.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CCT2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-10 ug/ml
  • Immunohistochemistry-Paraffin 1-5 ug/ml
  • Western Blot 1-2 ug/ml
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.08% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for TCP1-beta Antibody (F39 P7 F11) - BSA Free

• Cctb
• CCT-beta
• CCTBPRO1633,99D8.1
• chaperonin containing t-complex polypeptide 1, beta subunit
• chaperonin containing t-complex polypeptide 1, subunit 2
• chaperonin containing TCP1, subunit 2 (beta)
• MGC142074
• MGC142076
• T-complex protein 1 subunit beta
• T-complex protein 1, beta subunit
• TCP-1-beta

Background

The protein TCP-1 (t-complex polypeptide 1) is a subunit of the hetero-oligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species that are proposed to have independent functions in folding its in vivo substrates, the Actins and Tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCT2
• Uniprot:
  • P47207(C. elegans)