TBL1 Antibody

Immunohistochemistry-Paraffin: TBL1 Antibody [NB300-872] - Analysis in human Kidney shows preferential nuclear staining in the DCT. Antibody at 4 ug/mL. Steamed antigen retrieval with Tris/EDTA (pH 9), HRP-staining.

• Reactivity: Hu, Mu, Rt, Bv, Ca
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

TBL1 Antibody Summary

• Description: Novus Biologicals Goat TBL1 Antibody (NB300-872) is a polyclonal antibody validated for use in IHC and ELISA. Anti-TBL1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence SASDGSVCVLDLRK corresponding to C-Terminus according to NP_005638.1, NP_001132938.1, NP_001132939.1, NP_001132940.1, NP_078941.2.
• Specificity: This antibody is also expected to recognise the human protein TBLR1 (NP_078941), which is very similar. Variants (NP_005638.1; NP_001132938.1) encode isoform a (TBL1X) and variants (NP_001132939.1; NP_001132940.1 ) encode isoform b (TBLX1).
• Predicted Species: Mouse (100%), Rat (100%), Canine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TBL1X
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 4 - 6 ug/mL
  • Immunohistochemistry-Paraffin 4 - 6 ug/mL
  • Peptide ELISA Detection limit 1:4000
• Application Notes: IHC-P: Human kidney shows preferential nuclear staining in the DCT.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TBL1 Antibody

• EBI
• SMAP55
• TBL1transducin (beta)-like 1
• transducin (beta)-like 1X-linked
• X-linked

Background

Transducin beta-like protein 1 (TBL1) is part of an SMRT-containing complex. Mutation of the TBL1 gene is linked with human sensorineural deafness. TBL1 displays structural and functional similarities to Tup1 and Groucho corepressors, sharing their ability to interact with histone H3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TBL1 Antibody (NB300-872)(1)

Publication using NB300-872

• Bassi MT, Ramesar RS, Caciotti B et al. X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats. Am J Hum Genet 1999-06-01 [PMID: 10330347]

Bioinformatics

• Gene Symbol: TBL1X
• Entrez:
  • 6907(Human)
• Uniprot:
  • NP_005638.(Human)