TAS2R38 Antibody

Product Discontinued

TAS2R38 Antibody Summary

• Immunogen: A synthetic peptide from human TAS2R38 conjugated to blue carrier protein was used as the antigen.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAS2R38
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000
  • Immunohistochemistry-Paraffin 1:1000
  • Western Blot 1:1000

Reactivity Notes

Marmoset

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from whole serum
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for TAS2R38 Antibody

• PTCphenylthiocarbamide tasting
• T2R38
• T2R61PTC bitter taste receptor
• taste receptor type 2 member 38
• Taste receptor type 2 member 61
• taste receptor, type 2, member 38

Background

The STAS2R38 gene encodes a 333 amino acid long, 37 kDA taste receptor type 2 member 38 protein that obtains the ability to identify the perception of bitterness as it obtains the capabilities of tasting glucosinolates. Additionally, many believe that this receptor has the ability to stimulate alpha gustducin to regulate PLC-beta-2 activation. In doing so, it would lead to the gating of TRPM5. Therefore, the STAS2R38 gene is involved in taste transduction and bitter taste signaling. It has been researched regarding its role in thyroiditis, dental caries, nicotine dependence, motion sickness, phenylthiocarbamide tasting, coronary heart disease, alcoholism, and twining.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAS2R38