TARBP1 Antibody

Immunohistochemistry-Paraffin: TARBP1 Antibody [NBP1-03040] - Staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

Immunohistochemistry-Paraffin: TARBP1 Antibody [NBP1-03040] - Staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

Product Discontinued

TARBP1 Antibody Summary

• Immunogen: A 17 aa synthetic peptide near the center of human TARBP1. The immunogen is located within aa 1310 - 1360 of TARBP1.
• Epitope: Near the center
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TARBP1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Peptide affinity purified

Alternate Names for TARBP1 Antibody

• EC 2.1.1.-
• FLJ30482
• TAR (HIV-1) RNA binding protein 1
• TAR RNA loop binding protein
• TAR RNA-binding protein 1
• TAR RNA-binding protein of 185 kDa
• tardbp1
• TRM3probable methyltransferase TARBP1
• TRP-185TAR (HIV) RNA binding protein 1
• TRP185TAR (HIV) RNA-binding protein 1

Background

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TARBP1
• Entrez:
  • 6894(Human)
• Uniprot:
  • Q13395(Human)