t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric)

• Reactivity: Hu
• Applications: Func
• Suitable Sample Type: Cell Culture Supernatant, Plasma, Serum
• Standard Curve Range: 0.039 to 40.00 IU/mL
• Sensitivity: 0.034 IU/mL

t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric) Summary

• Description: Quality control test: Standard curve t-Plasminogen Activator/tPA (Human) Chromogenic Activity Assay Kit is developed to determine human PLAT activity.
• Standard Curve Range: 0.039 to 40.00 IU/mL
• Sensitivity: 0.034 IU/mL
• Assay Type: Colorimetric
• Sample Volume: 20 uL
• Kit Type: Activity Assay Kit (Colorimetric)
• Gene: PLAT

Applications/Dilutions

• Dilutions:
  • Functional

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric)

• Alteplase
• DKFZp686I03148
• EC 3.4.21
• EC 3.4.21.68
• plasminogen activator, tissue type
• plasminogen activator, tissue
• PLAT
• Reteplase
• tissue plasminogen activator (t-PA)
• tissue-type plasminogen activator
• TPA
• T-PA
• tPlasminogen Activator
• t-Plasminogen Activator

Background

Tissue-type plasminogen activator (tPA) is a 68-kDa serine protease that converts the zymogen plasminogen into the active serine protease plasmin, which digests fibrin and induces the dissolution of fibrin clots. tPA is synthesized by endothelial cells in normal blood vessels and displays relatively high affinity for fibrin, suggesting that it functions predominately in physiological thrombolysis in vivo.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

FAQs for t-Plasminogen Activator/tPA Kit (KA0974). (Showing 1 - 1 of 1 FAQ).

1. Please let me know the sensitivity of the tpA ELISA (Human)?
   • For this kit, the minimum detectable dose of tPA is typically < 0.08 IU/ml.

Bioinformatics

• Gene Symbol: PLAT