Syntaxin 1B Antibody (676204) [Alexa Fluor® 750]

• Applications: WB
• Clone: 676204
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

Syntaxin 1B Antibody (676204) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human Syntaxin 1B
  Lys2-Lys264
  Accession # P61266
• Specificity: Detects human Syntaxin 1B in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) Syntaxin 1A and 1B1 is observed, and no cross-reactivity with rhSyntaxin 5, 6, 7, 8, 12, or 16 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Syntaxin 1B/STX1B is an approximately 33 kDa member of the Syntaxin family.  It is a single-pass type IV transmembrane protein that is potentially involved in the docking of synaptic vesicles at presynaptic active zones. The cytoplasmic domain of Syntaxin 1B contains a coiled-coil Syntaxin domain (aa 29-180) which is implicated in the docking of synaptic vesicles with the presynaptic plasma membrane and a t-SNARE coiled coil domain (aa 191-253). Within the cytoplasmic domain, human Syntaxin 1B shares 100% aa sequence identity with mouse and rat Syntaxin 1B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.