Syntaxin 12 Antibody [Unconjugated]

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Syntaxin 12 was detected in immersion fixed paraffin-embedded sections of human brain using Goat Anti-Human/Mouse Syntaxin 12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6617) at 1 µg/mL for 1 ...read more
Syntaxin 12 was detected in perfusion fixed frozen sections of mouse brain (hippocampus) using Goat Anti-Human/Mouse Syntaxin 12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6617) at 15 µg/mL ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Host
Goat
Conjugate
Unconjugated

Order Details

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Catalog# & Formulation Size Price

Syntaxin 12 Antibody [Unconjugated] Summary

Immunogen
E.coli-derived recombinant human Syntaxin 12
Met1-Gln200
Accession # Q86Y82
Specificity
Detects human Syntaxin 12 in direct ELISAs. Detects human and mouse Syntaxin 12 in immunohistochemistry.
Source
N/A
Isotype
IgG
Host
Goat
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1-15 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Syntaxin 12 Antibody [Unconjugated]

  • MGC51957
  • STX12
  • STX13
  • STX14
  • Syntaxin 12
  • syntaxin-12

Background

Syntaxin 12/STX12 is a 39 kDa member of the Syntaxin family. It is a SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. Human STX12 is 276 amino acids (aa) in length, and is a type IV single-pass transmembrane protein. The cytoplasmic region extends from aa 1-248. A coiled-coil region extends from aa 33-131 within that region. From aa 178-240, there is a t-SNARE coiled-coil homology domain. The transmembrane region is located at 249-269, and a vesicular area is located at aa 270-276. Human STX12 shares 92% aa sequence identity with mouse STX12.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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