Recombinant Human Surf1 Protein

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SDS-Page: Surf1 Protein [NBP1-30315] - SURF1, 24.3 kDa (215aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human Surf1 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 80-273 of Human Surf1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
SURF1
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
24.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human Surf1 Protein

  • SURF-1
  • surfeit 1
  • surfeit locus protein 1

Background

SURF1, also known as surfeit 1, is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. This protein is localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. Defect in SURF1 is a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. Recombinant SURF1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol SURF1