Surf1 Products

Description

This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq]

Bioinformatics

Product By Gene ID	6834
Alternate Names	SURF-1 surfeit 1 surfeit locus protein 1

Research Areas for Surf1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Signal Transduction