ST6 Sialyltransferase 2/ST6GALNAC2 Antibody

Western Blot: ST6 Sialyltransferase 2/ST6GALNAC2 Antibody [NBP2-13392] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human cell line SK-MEL-30

Immunohistochemistry-Paraffin: ST6 Sialyltransferase 2/ST6GALNAC2 Antibody [NBP2-13392] - Staining of human spleen shows strong cytoplasmic and nuclear positivity in cells in red pulp.

Product Discontinued

ST6 Sialyltransferase 2/ST6GALNAC2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: DTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLL WGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPR DTPPKCIRCAV
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ST6GALNAC2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 30401951).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ST6 Sialyltransferase 2/ST6GALNAC2 Antibody

• (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B
• alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
• EC 2.4.99.-
• FLJ45660
• GalNAc alpha-2,6-sialyltransferase II
• SAITL1
• sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B
• sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase) B
• sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase)
• Sialyltransferase 7B
• sialyltransferase-like 1
• SIAT7
• SIAT7B
• SIAT7-B
• SIATL1
• ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 2
• ST6GalNAc II
• ST6GALNAC2
• ST6GalNAcII
• ST6GalNAII
• STHM
• STHM(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase

Background

ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ST6 Sialyltransferase 2/ST6GALNAC2 Antibody (NBP2-13392)(2)

Publications using NBP2-13392

• Mayr J, Lau K, Lai JCC et al. Unravelling the Role of O-glycans in Influenza A Virus Infection. Sci Rep. 2018-11-06 [PMID: 30401951] (ICC/IF, Human)
• Jia N, Barclay WS, Roberts K et al. Glycomic characterisation of respiratory tract tissues of ferrets: implications for its use in influenza virus infection studies. J Biol Chem. 2014-08-18 [PMID: 25135641] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: ST6GALNAC2