Somatostatin R2/SSTR2 Antibody (402038) [DyLight 755]

• Reactivity: Hu
• Applications: IHC, CyTOF-ready, Flow, ICC/IF
• Clone: 402038
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 755

Somatostatin R2/SSTR2 Antibody (402038) [DyLight 755] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: NS0 mouse myeloma cell line transfected with Somatostatin R2/SSTR2
  Met1-Ile369
  Accession # P30874
• Specificity: Detects human Somatostatin R2/SSTR2. Stains SSTR2 transfectants but not irrelevant transfectants.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SSTR2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Immunocytochemistry
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product MAB4224. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Somatostatin R2/SSTR2 Antibody (402038) [DyLight 755]

• Smstr2
• Somatostatin R2
• somatostatin receptor 2
• somatostatin receptor type 2
• SomatostatinR2
• SRIF-1
• SS2R
• SS-2-R
• SS2-R
• SST2
• SSTR2

Background

Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. Activation of these receptors by somatostatin--which is secreted by nerve and endocrine cells--regulates the secretion of insulin, glucagon and growth hormone, neuronal excitability in both the brain and the peripheral nervous system, and cell growth. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.

Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, as well as in the cerebrum and kidneys.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SSTR2