Somatostatin R2/SSTR2 Antibody (402038) [Phycoerythrin]

HEK293 human embryonic kidney cell line transfected with Somatostatin R2/SSTR2 and eGFP was stained with Mouse Anti-Human Somatostatin R2/SSTR2 PE-conjugated Monoclonal Antibody (Catalog # FAB4224P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: 402038
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Phycoerythrin

Somatostatin R2/SSTR2 Antibody (402038) [Phycoerythrin] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with Somatostatin R2/SSTR2
  Met1-Ile369
  Accession # P30874
• Specificity: Detects human Somatostatin R2/SSTR2. Stains SSTR2 transfectants but not irrelevant transfectants in flow cytometry.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SSTR2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Somatostatin R2/SSTR2 Antibody (402038) [Phycoerythrin]

• Smstr2
• Somatostatin R2
• somatostatin receptor 2
• somatostatin receptor type 2
• SomatostatinR2
• SRIF-1
• SS2R
• SS-2-R
• SS2-R
• SST2
• SSTR2

Background

Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Somatostatin R2/SSTR2 Antibody (FAB4224P)(2)

Publications using FAB4224P

• Yogindra Vedvyas, Enda Shevlin, Marjan Zaman, Irene M. Min, Alejandro Amor-Coarasa, Spencer Park et al. Longitudinal PET imaging demonstrates biphasic CAR T cell responses in survivors JCI Insight 2016-11-25 [PMID: 27882353]
• Yogindra Vedvyas, Enda Shevlin, Marjan Zaman, Irene M. Min, Alejandro Amor-Coarasa, Spencer Park et al. Longitudinal PET imaging demonstrates biphasic CAR T cell responses in survivors JCI Insight 2016-11-25 [PMID: 27882353] (Flow Cytometry, Mouse, Xenograft)

Bioinformatics

• Gene Symbol: SSTR2
• Uniprot:
  • P30874()