Sodium Potassium ATPase Alpha 2 Antibody [Allophycocyanin]

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Allophycocyanin

Sodium Potassium ATPase Alpha 2 Antibody [Allophycocyanin] Summary

• Immunogen: ATPase, Na+/K+ transporting, alpha 2(+) polypeptide. (Uniprot# P50993)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATP1A2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Sodium Potassium ATPase Alpha 2 Antibody [Allophycocyanin]

• alpha-A(+) catalytic polypeptide
• ATP1A2
• ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide
• ATPase, Na+/K+ transporting, alpha 2 polypeptide
• EC 3.6.3
• EC 3.6.3.9
• KIAA0778
• MGC59864
• MHP2
• migraine, hemiplegic 2
• Na(+)/K(+) ATPase alpha-2 subunit
• Na+/K+ ATPase, alpha-B polypeptide
• Sodium Potassium ATPase Alpha 2
• Sodium pump subunit alpha-2
• sodium/potassium-transporting ATPase alpha-2 chain
• sodium/potassium-transporting ATPase subunit alpha-2
• sodium-potassium ATPase

Background

The ubiquitously expressed sodium/potassium-ATPase exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motifs, sodium/potassium-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, alpha, beta and gamma, comprise to form the sodium/potassium-ATPase oligomer. The 113 kDa alpha subunit contains the binding sites for ATP and the cations. With a molecular weight between 40 and 60 kDa, the glycosylated beta subunit ensures correct folding and membrane insertion of the alpha subunits. The small 6 kDa gamma subunit co-localizes with the alpha subunit in nephron segments, where it increases the affinity of sodium/potassium-ATPase for ATP. The beta subunit, but not the gamma subunit, is essential for normal activity of sodium/potassium-ATPase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATP1A2