SNRPB Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: SNRPB Antibody [NBP2-56420] - Staining of human cell line HEK 293 shows localization to nucleoplasm.

Western Blot: SNRPB Antibody [NBP2-56420] - Analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1, using Anti-SNRPB antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, KD
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SNRPB Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QAPAGLAGPVRGVGGPSQQVMTPQGRGT
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SNRPB
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Knockdown Validated
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  SNRPB Recombinant Protein Antigen (NBP2-56420PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for SNRPB Antibody - BSA Free

• CODB polypeptide of Sm protein
• Sm protein B/B'
• small nuclear ribonucleoprotein polypeptides B and B'
• small nuclear ribonucleoprotein polypeptides B and B1
• small nuclear ribonucleoprotein-associated proteins B and B'
• SmB/B'
• Sm-B/B'sm-B/Sm-B'
• SmB/SmB'
• snRNP-Bsmall nuclear ribonucleoprotein polypeptide B
• SNRPB1

Background

SNRPB is encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SNRPB