SMARCA5/SNF2H Antibody [DyLight 350]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 350

SMARCA5/SNF2H Antibody [DyLight 350] Summary

• Immunogen: E. coli-derived recombinant human SAMRCA5/SNF2H
  Asp77-Val185
  Accession # O60264
• Specificity: Detects human SMARCA5/SNF2H in direct ELISAs. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SMARCA1 and rhSMARC4 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SMARCA5
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SMARCA5/SNF2H Antibody [DyLight 350]

• EC 3.6.1
• EC 3.6.4.-
• hISWI
• hSNF2HSWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5
• ISWI
• SMARCA5
• SNF2H
• SNF2Hsucrose nonfermenting-like 5
• subfamily a, member 5
• Sucrose nonfermenting protein 2 homolog
• SWI/SNF related, matrix associated, actin dependent regulator of chromatin
• SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 5
• WCRF135

Background

The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SNF2h/ISWI, also known as WCRF135, is the gene product of SMARCA5 that associates with WSTF (Williams Syndrome transcription factor) and several other nuclear proteins to mediate chromatin remodeling. SNF2h is also part of the NoRC (nucleolar remodeling complex).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SMARCA5