SLC39A10 Antibody

Product Discontinued

SLC39A10 Antibody Summary

• Immunogen: Antibody was raised against a 17 amino acid peptide near the center of the human ZIP10.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC39A10
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SLC39A10 Antibody

• DKFZp564L2123
• DKFZp781L10106
• FLJ90515
• KIAA1265
• LZT-Hs2
• MGC126565
• MGC138428
• solute carrier family 39 (metal ion transporter), member 10
• solute carrier family 39 (zinc transporter), member 10
• Solute carrier family 39 member 10
• zinc transporter ZIP10
• ZIP10
• ZIP-10
• Zrt- and Irt-like protein 10

Background

ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist. This antibody will not cross-react with the zinc transporter ZIP11.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC39A10
• Uniprot:
  • EDL99073(Rat)