SLC20A2 Antibody

Immunohistochemistry-Paraffin: SLC20A2 Antibody [NBP1-83360] - Staining of human duodenum shows strong membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: SLC20A2 Antibody [NBP1-83360] - Staining of human kidney shows moderate membranous positivity in cells in tubules.

Immunohistochemistry-Paraffin: SLC20A2 Antibody [NBP1-83360] - Staining of human testis shows moderate membranous positivity in cells in seminiferous ducts.

Immunohistochemistry-Paraffin: SLC20A2 Antibody [NBP1-83360] - Staining of human lymph node shows strong membranous positivity in germinal center cells.

Product Discontinued

SLC20A2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: NSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDTVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDAPE
• Predicted Species: Rat (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC20A2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for SLC20A2 Antibody

• Gibbon ape leukemia virus receptor 2
• Glvr-2
• GLVR2PIT-2
• hPit2
• MLVAR
• murine leukemia virus, amphotropic, receptor for
• Phosphate transporter 2
• pit2
• PiT-2
• sodium-dependent phosphate transporter 2
• solute carrier family 20 (phosphate transporter), member 2
• Solute carrier family 20 member 2

Background

Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC20A2 Antibody (NBP1-83360)(1)

Publication using NBP1-83360

• Kulesza T, Typiak M, Rachubik P et al. Hyperglycemic environment disrupts phosphate transporter function and promotes calcification processes in podocytes and isolated glomeruli Journal of cellular physiology 2022-02-12 [PMID: 35150131] (IF/IHC)

Bioinformatics

• Gene Symbol: SLC20A2