SIRP beta 1/CD172b Antibody (308908) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 308908
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

SIRP beta 1/CD172b Antibody (308908) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human SIRP beta 1/CD172b in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SIRP beta 1/CD172b Antibody (308908) [Alexa Fluor™ Plus 647]

• CD172 antigen-like family member B
• CD172b antigen
• CD172b
• DKFZp686A05192
• FLJ26614
• signal-regulatory protein beta 1
• signal-regulatory protein beta-1
• SIRP beta 1
• SIRPB1
• SIRP-beta-1 isoform 3
• SIRP-BETA-1

Background

SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains. Unlike SIRP alpha that has cytoplasmic ITIM domains, SIRP beta 1 possesses positively charged residues that allow association with ITAM motif containing adaptor molecules. SIRP beta 1 is expressed on cells of monocyte, macrophage or dendritic lineages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.