SIPA1L2 Antibody - BSA Free

Western Blot: SIPA1L2 Antibody [NBP1-77090] - Analysis of SIPA1L2 in rat brain tissue lysate with SIPA1L2 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry-Paraffin: SIPA1L2 Antibody [NBP1-77090] - Human brain tissue with SIPA1L2 antibody at 5 ug/ml.

Immunocytochemistry/ Immunofluorescence: SIPA1L2 Antibody - BSA Free [NBP1-77090] - Immunofluorescence of SIPA1L2 in human brain tissue with SIPA1L2 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

SIPA1L2 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1L2. The immunogen is located within the first 50 amino acids of SIPA1L2. Amino Acid Squence: SKFKDPPRIMQSDDYFARK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SIPA1L2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 0.5-1 ug/ml
• Control Peptide:

  SIPA1L2 Peptide (NBP1-77090PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for SIPA1L2 Antibody - BSA Free

• FLJ23632
• signal-induced proliferation-associated 1 like 2
• signal-induced proliferation-associated 1-like protein 2
• SIPA1-like protein 2
• SPA-1-like 2
• SPAL2

Background

Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SIPA1L2
• Uniprot:
  • NP_065859(Human)