Human, Mouse, Rat SHIP ELISA Kit (Colorimetric)

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ELISA
Suitable Sample Type
Attached Cell, Loosely Attached Cell, Suspension Cell
Standard Curve Range
> 5000 Cells
Sensitivity
n/a

Order Details

Human, Mouse, Rat SHIP ELISA Kit (Colorimetric) Summary

Description
INPP5D (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of INPP5D expression in cultured cells.
Standard Curve Range
> 5000 Cells
Sensitivity
n/a
Assay Type
Indirect ELISA kit (Cell-Based)
Sample Volume
n/a
Kit Type
ELISA Kit (Colorimetric)
Gene
INPP5D

Applications/Dilutions

Application Notes
INPP5D (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of INPP5D expression in cultured cells.
Theoretical MW
145 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using KA3244.

Packaging, Storage & Formulations

Storage
Store at 4C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human, Mouse, Rat SHIP ELISA Kit (Colorimetric)

  • 145kD
  • EC 3.1.3
  • hp51CNMGC142142
  • Inositol polyphosphate-5-phosphatase of 145 kDa
  • inositol polyphosphate-5-phosphatase, 145kDa
  • INPP5D
  • MGC104855
  • SHIP
  • SHIPMGC142140

Background

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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KA3244
Species: Hu, Mu, Rt
Applications: ELISA

Publications for SHIP ELISA Kit (KA3244)(1)

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Blogs on SHIP.

Getting SHIP-shape Over Tumour Suppression
PTEN antibodies have shown PTEN to be an important tumor suppressor and, in mutated form, a factor in cancer development. However, a recent study, led by Robert Rickert, shows that the SHIP gene may also be an important tumor suppressor in B-cell lymp...  Read full blog post.

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Bioinformatics

Gene Symbol INPP5D