Human, Mouse, Rat SHIP ELISA Kit (Colorimetric)

• Reactivity: Hu, Mu, Rt
• Applications: ELISA
• Suitable Sample Type: Attached Cell, Loosely Attached Cell, Suspension Cell
• Standard Curve Range: > 5000 Cells
• Sensitivity: n/a

Human, Mouse, Rat SHIP ELISA Kit (Colorimetric) Summary

• Description: INPP5D (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of INPP5D expression in cultured cells.
• Specificity: INPP5D (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of INPP5D expression in cultured cells.
• Standard Curve Range: > 5000 Cells
• Sensitivity: n/a
• Assay Type: Indirect ELISA kit (Cell-Based)
• Sample Volume: n/a
• Kit Type: ELISA Kit (Colorimetric)
• Gene: INPP5D

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at 4C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human, Mouse, Rat SHIP ELISA Kit (Colorimetric)

• 145kD
• EC 3.1.3
• hp51CNMGC142142
• Inositol polyphosphate-5-phosphatase of 145 kDa
• inositol polyphosphate-5-phosphatase, 145kDa
• INPP5D
• MGC104855
• SHIP
• SHIPMGC142140

Background

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for SHIP ELISA Kit (KA3244)(1)

Publication using KA3244

• Ali MA, Eid RMHM, Hanafi MY. et al. Vitamin C and E chronic supplementation differentially affect hepatic insulin signaling in rats. Life Sci 2018-02-01 [PMID: 29291420]

FAQs for SHIP ELISA Kit (KA3244). (Showing 1 - 1 of 1 FAQ).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: INPP5D