SHIP Products

Antibodies
SHIP Antibody (257812)
SHIP Antibody (257812)
MAB2317
Species: Hu, Mu, Rt
Applications: WB, ICC
Host: Rat Monoclonal
SHIP Antibody
SHIP Antibody
NBP2-49633
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
SHIP Antibody
SHIP Antibody
NB100-91958
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
ELISA Kits
SHIP ELISA Kit [HRP]
SHIP ELISA Kit [HRP]
KA3244
Species: Hu, Mu, Rt
Applications: WB, ELISA
Lysates
SHIP Overexpression Lysate (N ...
SHIP Overexpression Lysate (Native)
NBL1-12000
Applications: WB
Proteins
SHIP Recombinant Protein Anti ...
SHIP Recombinant Protein Antigen
NBP2-49633PEP
Species: Hu
Applications: AC
RNAi
SHIP RNAi
SHIP RNAi
H00003635-R02
Species: Hu
SHIP RNAi
SHIP RNAi
H00003635-R01
Species: Hu

Description

SH2-containing inositol phosphatase 1 (SHIP) is a 145 kDa hemopoietic-specific phosphatase that hydrolyzes phosphatidylinositol-3,4,5-triphosphate to phosphatidylinositol-3, 4-bisphosphate. SHIP has been shown to bind directly a phosphorylated motif, immunoreceptor tyrosine-based inhibition motif (ITIM), present in the cytoplasmic domain of FcgammaRIIB1 (1). Also, results demonstrate that FcgammaRIIB use SHIP1 to inhibit pathways shared by receptor tyrosine kinases and immunoreceptors to trigger cell proliferation and cell activation, respectively (2).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 3635
Alternate Names
  • EC 3.1.3
  • 145kD
  • Inositol polyphosphate-5-phosphatase of 145 kDa
  • hp51CNMGC142142
  • SHIPMGC142140
  • MGC104855
  • inositol polyphosphate-5-phosphatase, 145kDa

Pathways for SHIP

View related products by pathway and learn more about each of the pathways below.

Hypersensitivity
Regulation Of Gene Expression
Response To Cisplatin
Pathogenesis
Localization
Chromatin Remodeling

Research Areas for SHIP

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology
Phospho-Specific
Signal Transduction

PTMs for SHIP

Learn more about PTMs related to SHIP.

Phosphorylation

Bioinformatics Tool for SHIP

Discover related pathways, diseases and genes to SHIP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related SHIP Blog Posts

Check out the latest blog posts on SHIP.
Getting SHIP-shape Over Tumour Suppression
PTEN antibodies have shown PTEN to be an important tumor suppressor and, in mutated form, a factor in cancer development. However, a recent study, led by Robert Rickert, shows that the SHIP gene may also be an important tumor suppressor in B-cell lymp...    Read more.
Read more SHIP related blogs.