Serpin B8/Proteinase Inhibitor 8 Antibody [Alexa Fluor® 750]

• Reactivity: Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 750

Serpin B8/Proteinase Inhibitor 8 Antibody [Alexa Fluor® 750] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Serpin B8/Proteinase Inhibitor 8
  Asp2-Pro374
  Accession # O08800
• Specificity: Detects mouse Serpin B8/Proteinase Inhibitor 8 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Serpin B8, rhSerpin B9, and rhSerpin B6 is observed and less than 1% cross-r
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin B8/Proteinase Inhibitor 8 Antibody [Alexa Fluor® 750]

• CAP2
• CAP-2
• CAP2clade B (ovalbumin), member 8
• Cytoplasmic antiproteinase 2
• NK10
• Peptidase inhibitor 8
• PI8
• PI-8
• protease inhibitor 8 (ovalbumin type)
• Serpin B8
• serpin peptidase inhibitor, clade B (ovalbumin), member 8

Background

Serpin B8, also known as Proteinase Inhibitor 8 (PI8) and cytoplasmic antiproteinase 2 (CAP2), is a member of the Serpin superfamily of the serine protease inhibitors (1). It inhibits furin, a ubiquitously expressed convertase that processes many pro-proteins (2). Distribution of Serpin B8 alters during kidney regeneration, indicating that it plays a role in inflammation or tissue repair (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.