SERBP1 Antibody (SERBP1/3491)

Western Blot: SERBP1 Antibody (SERBP1/3491) [NBP3-07610] - Western Blot Analysis of K562 and PC3 cell lysate using SERBP1 Mouse Monoclonal Antibody (SERBP1/3491).

Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3491) [NBP3-07610] - Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with SERBP1 Mouse Monoclonal Antibody (SERBP1/3491).

Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3491) [NBP3-07610] - Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with SERBP1 Mouse Monoclonal Antibody (SERBP1/3491).

Protein Array: SERBP1 Antibody (SERBP1/3491) [NBP3-07610] - Analysis of Protein Array containing more than 19,000 full-length human proteins using SERBP1 Mouse Monoclonal Antibody (SERBP1/3491).

• Reactivity: Hu
• Applications: WB, IHC, MA
• Clone: SERBP1/3491
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

SERBP1 Antibody (SERBP1/3491) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08560)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
• Immunogen: Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary) (Uniprot: Q8NC51)
• Localization: Cytoplasm and nucleus. Also found in perinuclear regions.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SERBP1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1-2 ug/ml
  • Protein Array
  • Western Blot 1-2 ug/ml
• Application Notes: Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
  Optimal dilution for a specific application should be determined.
• Theoretical MW: 60 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for SERBP1 Antibody (SERBP1/3491)

• CGI-55
• CHD3IP
• chromodomain helicase DNA binding protein 3 interacting protein
• DKFZP564M2423
• HABP4L
• PAI-1 mRNA binding protein
• PAI1 RNA-binding protein 1
• PAI-RBP1DKFZp564M2423
• PAIRBP1FLJ90489
• plasminogen activator inhibitor 1 RNA binding protein
• plasminogen activator inhibitor 1 RNA-binding protein
• SERPINE1 mRNA binding protein 1
• SERPINE1 mRNA-binding protein 1

Background

SERBP1 may play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of messagedecay

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERBP1
• Uniprot:
  • Q8NC51(Human)