Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.
Alternate Names for SEC22B Antibody
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
SEC22 vesicle trafficking protein-like 1 (S. cerevisiae)
SEC22 vesicle trafficking protein-like 1
SEC22 vesicle-trafficking protein homolog B
SEC22 vesicle-trafficking protein-like 1
SEC22, vesicle trafficking protein (S. cerevisiae)-like 1
SEC22L1ER-Golgi SNARE of 24 kDa
vesicle-trafficking protein SEC22b
The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript. FUNCTION: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. SUBUNIT: Component of two distinct SNARE complexes consisting of STX5, GOSR2/BOS1, BET1 and SEC22B or STX18, USE1L, BNIP1/SEC20L and SEC22B. YKT6 can probably replace SEC22B in either complex. SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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