SDHA Antibody (1084056) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clone: 1084056
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

SDHA Antibody (1084056) [Alexa Fluor® 750] Summary

• Immunogen: Synthetic Peptide
  Accession # P31040
• Specificity: Detects a synthetic peptide corresponding to residues near amino acid 610 of human SDHA protein by Direct ELISA.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SDHA Antibody (1084056) [Alexa Fluor® 750]

• CMD1GG
• flavoprotein subunit of complex II
• FP
• MC2DN1
• NDAXOA
• PGL5
• PPGL5
• SDH1
• SDH2
• SDHA
• SDHF
• succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

Background

SDHA is 73 kDa protein located on the inner membrane of the mitochondria which participates in both the citric acid cycle and the respiratory chain. SDHA is one subunit of the SDH complex, which contains 4 total subunits, that are encoded by nuclear genes.  All the SDH genes are involved in the tumorigenesis of different types of cancers. Germline SDHA mutations are a driver for multiple types of cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.