SAV1 Antibody

Product Discontinued

SAV1 Antibody Summary

• Immunogen: Peptide with sequence DHTNKKAQYRHPC corresponding to internal region according to NP_068590.1.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SAV1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
• Application Notes: WB: Preliminary experiments gave an approx. 37 kDa band in human kidney lysates after 0.1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 44.6 kDa band according to NP_068590.1. The 37 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for SAV1 Antibody

• 45 kDa WW domain protein
• hWW45
• protein salvador homolog 1
• salvador homolog 1 (Drosophila)
• SAV
• WW domain-containing
• WW45salvador
• WWP4,1700040G09Rik

Background

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously expressed in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SAV1 Antibody (NBP1-20970)(1)

Publication using NBP1-20970

• Yoo NJ, Soung YH, Lee JW et al. Mutational analysis of salvador gene in human carcinomas. APMIS 2003-06-01 [PMID: 12969014]

Bioinformatics

• Gene Symbol: SAV1
• Entrez:
  • 60485(Human)
  • 64010(Mouse)
  • 299116(Rat)
• Uniprot:
  • NP_068590.1(Human)