RSK2 Antibody

Immunohistochemistry: RSK2 Antibody [NBP1-19295] - Human pancreas tissue stained with p90/RSK2, pAb at 20ug/ml.

Immunohistochemistry: RSK2 Antibody [NBP1-19295] - Human tonsil tissue stained with p90/RSK2, pAb at 20ug/ml.

Product Discontinued

RSK2 Antibody Summary

• Immunogen: Synthetic peptide derived from the sequence of mouse RSK2, conjugated to KLH
• Specificity: p90/RSK2
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RPS6KA3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:100-1:2000

Reactivity Notes

Human, Mouse, Rat, Bovine, Canine, Chicken, Guinea Pig, Monkey, Pig, Rabbit, Sheep.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.2, containing 50% glycerol.
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for RSK2 Antibody

• 90 kDa ribosomal protein S6 kinase 3
• CLS
• Coffin-Lowry syndrome
• EC 2.7.11
• EC 2.7.11.1
• HU-3
• Insulin-stimulated protein kinase 1
• ISPK1
• ISPK-1
• MAP kinase-activated protein kinase 1b
• MAPK-activated protein kinase 1b
• MAPKAP kinase 1b
• MAPKAPK1B
• MAPKAPK-1b
• mental retardation, X-linked 19
• MRX19
• p90-RSK2
• p90RSK3
• pp90RSK2
• ribosomal protein S6 kinase alpha-3
• ribosomal protein S6 kinase, 90kD, polypeptide 3
• ribosomal protein S6 kinase, 90kDa, polypeptide 3
• Ribosomal S6 kinase 2
• RPS6KA3
• RSK
• RSK2
• RSK-2
• RSK2p90-RSK 3
• S6K-alpha3
• S6K-alpha-3

Background

Ribosomal protein S6 kinase II (RSK2) is a protein serine/threonine kinase that was originally detected by its ability to catalyze the multi-site phosphorylation of the 40S ribosomal protein S6 in vitro. One of the important substrates of RSK may be the Glycogenbinding subunit of Protein phosphatase-1, which when phosphorylated by RSK, appears to activate Protein phosphatase 1. This results in increased dephosphorylation and activation of Glycogen synthase to enhance Glycogen synthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RSK2 Antibody (NBP1-19295)(1)

Publication using NBP1-19295

• Jiang FF, Wang RQ, Guo CY et al. Phospho-proteomics identifies a critical role of ATF2 in pseudorabies virus replication Virologica Sinica 2022-06-07 [PMID: 35688418] (WB, Bovine, Porcine)

Bioinformatics

• Gene Symbol: RPS6KA3
• Entrez:
  • 6197(Human)
  • 110651(Mouse)
  • 81771(Rat)