RPLP0 Antibody

Product Discontinued

RPLP0 Antibody Summary

• Immunogen: The immunogen for this product maps to a region between residue 100 and 150 of human Ribosomal Protein, Large, P0 using the numbering given in entry NP_444505.1 (GeneID 6175).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RPLP0
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for RPLP0 Antibody

• 60S acidic ribosomal protein P0
• 60S ribosomal protein L10E
• acidic ribosomal phosphoprotein P0
• L10E
• MGC111226
• MGC88175
• P0
• PRLP0
• ribosomal protein, large, P0
• RPP0

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RPLP0 Antibody (NBP1-49979)(1)

Publication using NBP1-49979

• Kapadia M, Bijelic D, Zhao H et al. Effects of sustained icv infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling Acta Neuropathologica CommunicationsNeuroscience of Disease 2017-09-07 [PMID: 28882191] (Mouse)

Bioinformatics

• Gene Symbol: RPLP0