RNPS1 Antibody [Janelia Fluor® 646]

Product Discontinued

RNPS1 Antibody [Janelia Fluor® 646] Summary

• Immunogen: RNA binding protein S1, serine-rich domain. (Uniprot# Q15287)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RNPS1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for RNPS1 Antibody [Janelia Fluor® 646]

• E5.1
• LDC2
• MGC117332
• RNA binding protein S1, serine-rich domain
• RNA-binding protein S1, serine-rich domain
• RNA-binding protein with serine-rich domain 1
• SR protein
• SR-related protein LDC2

Background

RNPS1 encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RNPS1