RNF168 Antibody [Biotin]

• Reactivity: Hu, Mu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Biotin

RNF168 Antibody [Biotin] Summary

• Immunogen: E. coli-derived recombinant mouse RNF168
  Asn423-Arg565
  Accession # Q80XJ2
• Specificity: Detects recombinant mouse RNF168 and recombinant human RNF168 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: RNF168
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for RNF168 Antibody [Biotin]

• E3 ubiquitin-protein ligase RNF168
• EC 6.3.2
• EC 6.3.2.-
• FLJ39749
• ring finger protein 168FLJ35794
• RNF168

Background

The complex repair response elicited by DNA double-strand breaks (DSBs) includes recruitment of several DNA repairproteins and ubiquitination of H2A-type histones (see MIM 142720). RNF168 is an E3 ubiquitin ligase critical for DSBrepair (Stewart et al., 2009 (PubMed 19203578)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RNF168