RKIP/PBP Antibody Pair

Product Discontinued

RKIP/PBP Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00005037-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human PEBP1.
  
  
• Capture antibody: mouse monoclonal anti-PEBP1 IgG1 Kappa (100 ug)
• Detection antibody: biotinylated mouse monoclonal anti-PEBP1 IgG2b Kappa (50 ug)
• Standard Curve Range: 0.1 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: PEBP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 0.1 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RKIP/PBP Antibody Pair

• HCNP
• HCNPpp
• hippocampal cholinergic neurostimulating peptide
• Neuropolypeptide h3
• PBP
• PBPPEBP-1
• PEBP1
• PEBP-1
• PEBPHCNPpp
• phosphatidylethanolamine binding protein 1
• phosphatidylethanolamine-binding protein 1
• prostatic binding protein
• Prostatic-binding protein
• Raf kinase inhibitory protein
• RKIP
• RKIPRaf kinase inhibitor protein

Background

PBP, also known as RKIP (RAF kinase inhibitor protein), binds ATP, opioids and phosphatidylethanolamine. PBP is able to regulate Aurora kinase B expression and the spindle checkpoint through interaction with the RAF1/MEK/ERK cascade. PBP is able to bind to RAF1 and MEK and competitively disrupt the interaction between these proteins. PBP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. It increases the production of choline acetyltransferase but not acetylcholinesterase. PBP has been implicated as a suppressor of metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PEBP1