Rit1 Antibody (456201) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: 456201
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Rit1 Antibody (456201) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human Rit1
  Met1-Thr219
  Accession # Q92963
• Specificity: Detects human Rit1 in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rit1 Antibody (456201) [Alexa Fluor® 488]

• GTP-binding protein Rit1
• GTP-binding protein Roc1
• MGC125864
• MGC125865
• Ras-like protein expressed in many tissues
• Ras-like without CAAX 1
• Ras-like without CAAX protein 1
• RIBB
• RIBBRIT
• Ric-like, expressed in many tissues
• RIT
• Rit1
• ROC1
• ROC1Ric (Drosophila)-like, expressed in many tissues

Background

Rit1 is a member of the Ras-related small GTPase superfamily. The 219 amino acid, 25 kDa human Rit1 is a cytoplasmic cell membrane-associated protein that is expressed in most tissues. It is widely expressed in the developing and adult nervous systems and participates in NGF-induced axon outgrowth. Rit1 forms complexes with other small GTPases, such as cdc42 and Rac1, that are important during cell growth and polarity. Human Rit1 shares 95% amino acid identity with mouse and rat Rit1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.