RhoB Antibody - BSA Free

Images

 
Immunohistochemistry: RhoB Antibody - BSA Free [NBP3-46738] - Immunohistochemistry of paraffin-embedded human stomach tissue slide using ( RhoB Antibody) at dilution of 1:50
Western Blot: RhoB Antibody - BSA Free [NBP3-46738] - HEK-293 cells were subjected to SDS PAGE followed by western blot with (RhoB antibody) at dilution of 1:1000

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

RhoB Antibody - BSA Free Summary

Immunogen
ras homolog gene family, member B. (Uniprot# P62745)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RHOB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 1:50 - 1:100
  • Western Blot 1:500 - 1:2000
Theoretical MW
22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 50% Glycerol, pH (7.3)
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for RhoB Antibody - BSA Free

  • ARH6MSTP081
  • ARHBAplysia RAS-related homolog 6
  • h6
  • MST081
  • oncogene RHO H6
  • ras homolog gene family, member B
  • Rho cDNA clone 6
  • RHOH6RhoB
  • rho-related GTP-binding protein RhoB

Background

Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for RhoB Antibody (NBP3-46738) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for RhoB Antibody (NBP3-46738) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for RhoB Antibody (NBP3-46738)

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Blogs on RhoB.

Suppressing breast cancer metastasis: The role of hypoxia-induced RhoB expression and activation
By Jamshed Arslan, Pharm. D., PhD. The Ras homologous (Rho) GTPase family of signaling molecules has over 20 members, which typically cycle between active (GTP-bound) and inactive (GDP-bound) states. These small GTPa...  Read full blog post.

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Bioinformatics

Gene Symbol RHOB