RGC32 Antibody

ELISA: RGC32 Antibody [44450002]

Product Discontinued

RGC32 Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein.
• Specificity: This product is specific for Human C13orf15.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RGCC
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot. Use in Immunohistochemistry reported in scientific literature (PMID:31853279).

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for RGC32 Antibody

• bA157L14.2
• chromosome 13 open reading frame 15
• KIAA0564
• RGC-32MGC87338
• RGC32response gene to complement 32 protein

Background

This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RGC32 Antibody (44450002)(4)

Publications using 44450002

• Zhang J, Lei J, Yuan L et al. Response gene to complement 32 promotes cell survival via the NF kappa B pathway in non small cell lung cancer Exp Ther Med 2019-11-08 [PMID: 31853279] (IF/IHC, Human)
• Counts SE, Mufson EJ. Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease Cell Transplant. 2017-04-13 [PMID: 27938491] (WB, Human)
• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: RGCC
• Entrez:
  • 28984(Human)
• Uniprot:
  • Q9H4X1(Human)