RGC32 Products

Description

RGC32 is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq]

Bioinformatics

Entrez	28984 Human
Uniprot	NM_014059 Human NP_054778 Human Q9H4X1 Human
Product By Gene ID	28984
Alternate Names	bA157L14.2 chromosome 13 open reading frame 15 KIAA0564 RGC-32MGC87338 RGC32response gene to complement 32 protein

Research Areas for RGC32

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication